The study, co-led by Sattva Neelapu, M.
Median overall survival was not reached, and no axi-cel related adverse effects were reported after the month period. The results mirrored findings of a previously reported median follow up of In addition, exploratory analyses were performed to assess CAR T-cell persistence and B-cell recovery in patients with ongoing remission, and at 24 months, persisting CAR gene-marked cells were observed in 66 percent of patients with evaluable biomarker samples.
Peripheral blood B-cells were measurable in 75 percent of patients. The real-world retrospective study included 17 centers that contributed data independent from the manufacturer-funded trial. Findings from the study, led by Loretta Nastoupil, M. By day 90, the real-world assessment reported 81 percent of patients had an objective response and 57 percent had a complete response. Note: material may have been edited for length and content.
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Pre-operative urinary cathepsin D is associated with survival in patients with renal cell carcinoma
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When Stephen Jay Gould, a revolutionary evolutionary biologist and paleontologist, was diagnosed with peritoneal mesothelioma , he learned the median survival was just 8 months after diagnosis. At his very core, Gould was a researcher and loved statistics.
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After poring over the most recent medical journals and studies, he found relief in these numbers. Though the median survival was shockingly short, he realized the odds were in his favor to fall on the other side of the median and potentially live for years. Gould went on to have a prolific scientific career, living 20 years after his initial diagnosis. Along with colleague Niles Eldredge, Gould developed his theory of punctuated equilibrium, meaning evolution has long periods of stability with punctuated periods of change and development.
Cancer survivors: Managing your emotions after cancer treatment - Mayo Clinic
He also became well known publicly for his articles on various subjects in a column for Natural History magazine, as well as his books and various television appearances including The Simpsons in In , the Library of Congress named him a Living Legend for his activism and contributions to evolutionary biology. In addition to his major scientific contributions, Gould became a beacon of hope for mesothelioma patients and other cancer patients that they could beat the odds with the proper attitude. Mesothelioma is a rare cancer caused by exposure to asbestos. Asbestos is a mineral that was widely used for centuries because of its fire resistance and durability.
The mineral could be found in everything from construction materials like roofing shingles to protective clothing and automotive parts. If any of these materials become damaged, the dangerous asbestos fibers can easily be inhaled or ingested. The cabinets that held the specimens were protected with an asbestos lining.